Ghana and Arsenal have suffered a major injury blow as Thomas Partey was subbed off at half-time in the 3-0 defeat to Aston Villa.
The 28-year-old is likely to miss Ghana’s double-header against Sudan next week.
The £45million signing had earned rave reviews for his performance in the 1-0 win against Manchester United last week.
But the Ghana international did not immediately emerge with the rest of the Arsenal team after the break against Aston Villa.
With his side trailing 1-0 at half-time, it was then announced the defensive midfielder would be replaced by Dani Ceballos.
Reports inside the ground pointed to a possible thigh injury sustained in the first-half.
It is not yet clear how serious the injury is, although Partey later took his place on the Arsenal bench.
Things went from bad to worse for the Gunners as Ollie Watkins struck two second-half goals against a poor Arsenal defence.